1476, Florence. Giovanni Auditore, an assassin, attempts to thwart a conspiracy against one of Lorenzo de Medicis allies. The ensuing inquiry will take him to Milan where he tries to prevent the worst from happening.
Pursuing Sforza's assassin's, Giovanni arrives in Venice where he intercepts a coded letter from the members of the conspiracy. Decoding this document in order to get to the top of the conspiracy becomes of extreme importance.
Unable to decode the letter, Giovanni decides to deliver it to Rome in order to unmask the ringleaders. But there he discovers that the conspiracy is much more widespread and dangerous than he thought.
Romano Orzari
Giovanni Auditore
Manuel Tadros
Rodrigo Borgia
Jesse Rath
Federico Auditore
Devon Bostick
Ezio Auditore da Firenze
Alex Ivanovici
Lorenzo Medici
Michel Perron
Uberto Alberti
Arthur Grosser
Pope Sixtus IV
Peter Miller
Galeazzo Maria Sforza
Harry Standjofski
Silvio Barbarigo
Frank Fontaine
Marco Barbarigo
Shawn Baichoo
Monk Maffei
Claudia Ferri
Maria Auditore
Devery Jacobs
Claudia Auditore
Patrick Kerton
Lampugnari
Marcello Bezina
Monk/Servant
Bianca LeBlanc
Ezio's Girlfriend
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